Search on: HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES 
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Descriptor English:   Hypoxia-Inducible Factor-Proline Dioxygenases 
Descriptor Spanish:   Prolina Dioxigenasas del Factor Inducible por Hipoxia 
Descriptor Portuguese:   Prolina Dioxigenases do Fator Induzível por Hipóxia 
Tree Number:   D08.811.682.690.416.617.500
D08.811.682.690.708.694.500
Definition English:   Dioxygenase enzymes that specifically hydroxylate a PROLINE residue on the HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. They are OXYGEN-dependent enzymes that play an important role in mediating cellular adaptive responses to HYPOXIA. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   55296 
Unique Identifier:   D064799 

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